Comparative Studies of Penicillinase Induction in Microorganisms by Natural and Semi- Synthetic Penicillins
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چکیده
منابع مشابه
Isolation of a Penicillin Acylase Producing E.coli and Kinetic Characterization of the Whole Cell Enzyme Activity
Penicillin acylase (EC 3.5.1.11) has been a target of study for a long time because of its pivotal role in the deacylation of the penicillin into the 6- aminopenicillanic acid (6-APA) and the side-chain organic acids. This property of penicillin acylase has been exploited commercially for large scale production of 6-APA, which is the key intermediate in the manufacture of semi-synthetic penicil...
متن کاملانجام آمیختگی مصنوعی در باکتری اشریشیاکلی جهت بررسی انتقال پلاسمید مولد پنی سیلیناز
Conjugation is a major mechanism of DNA transfer among bacteria which takes place in both laboratory and natural environment and brings about new characteristics. Extrachromosomal DNA called plasmid are important elements in this exchange. Resistance plasmid confer resistance to many antibiotics and in this group, penicillinase plasmid is responsible for resistance to penicillins and cephalos...
متن کاملIsolation of a Penicillin Acylase Producing E.coli and Kinetic Characterization of the Whole Cell Enzyme Activity
Penicillin acylase (EC 3.5.1.11) has been a target of study for a long time because of its pivotal role in the deacylation of the penicillin into the 6aminopenicillanic acid (6-APA) and the side-chain organic acids. This property of penicillin acylase has been exploited commercially for large scale production of 6-APA, which is the key intermediate in the manufacture of semi-synthetic penicilli...
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Phytohormones, of which indole-3-acetic acid (IAA) is most widely recognized, are naturally occurring compounds which regulate plant growth activities. Other plant growth-regulating compounds, such as 2,4,5-trichlorophenoxyacetic acid (2,4, 5-T), differ in that they are chemically synthesized. There are indications that both natural and synthetic plant growth regulators have significant activit...
متن کاملScreening and isolation of penicillinase inhibitor, KA-107.
It is known that penicillin resistance of bacteria is mainly caused by the inactivation of penicillin by penicillinase derived from such strains. We have developed a screening procedure for penicillinase inhibitors. Several microorganisms were found to produce such inhibitors, and from the culture filtrate of Streptomyces gedanensis ATCC 4880 a penicillinase inhibitor, named KA-107, was isolate...
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